Patients who suffer from autoimmune disease accept chronic management of symptoms through nonspecific immunosuppressant as the standard of treatment. These treatments along with medications ranging from cyclophosphamide to biologic therapies are associated with an increased risk for infections as well as significant adverse effects including hepatotoxicity, gastrointestinal perforation, and fatigue.
An optimal treatment strategy for autoimmune disease would specifically target disease associated antigens and limit systemic side effects. Many recent approaches have focused on the development of curative, antigen specific immunotherapies (ASI); however, the market has seen little clinical success. Promising animal studies of ASI have not yet been translated into clinical efficacy.
As such, world-leading immunologists have voiced that a new delivery mechanism that maximizes efficacy is necessary to push the first antigen-specific therapy through FDA approval.
An engineered nanoparticle that delivers dual therapeutic agents to the right place at the right time.
Because of the spatial and temporal control, we achieve better results in addition to lowering concentration, frequency, and side effects.
Spatiotemporally Tuned Particles
Statera’s patented technology, Spatiotemporally Tuned Particles (STP), adds targeting and temporal control to the otherwise free floating drug agents. In encapsulating drug agents in STP, we can achieve optimized, sequential delivery to specific cell targets. STP has been shown to supersede the efficacy of the current standard of combinatorial drug delivery.
Meet Our Team
Owen Yang, MBA
Passionate Healthcare Entrepreneur. MBA graduate from Yale University; 5+ years experience in healthcare technology, overseeing business strategy and implementation, and experience in private equity, investments ranging from $10M to $25M. Recipient of the Yale Marshall and Jay S. Yadav, M.D. Entrepreneurial Fellowship Award.
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